January 17, 2024
During the meeting, the following key points were discussed:
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Dr Doug: because of the awesome response. And you guys are so amazing. We have too many questions to answer in an hour. So what I'm having my team do is to go through all the questions as they come in, and then they're sort of lumping them the same topics, because we get a lot of the same, repeat questions, lumping them together. So I make sure that I hit those topics, and then what we'll do is if your question isn't answered. What I suggest that you do is to put it into the slack channel. Has everybody been on the slack channel, and I get a thumbs up.
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Dr Doug: Oh, yeah. So I know slack's not for everyone, and I get it, if it seems intimidating but it is a really good way to communicate. So if you don't get your question answered, drop it in the slack channel. We'll see if anybody else can answer it, cause that could get you an answer quickly, and then, if not, then we hopefully we can drop back into the next week, and we can get it answered. So we're trying to find a way to answer as many of the same questions as possible.
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Dr Doug: So I'll pull that document up. But we'll go through that. And then I also wanted to announce, if you guys have been on the Youtube channel, you've seen the videos coming out about vibration plates. Yeah. So
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Dr Doug: The the interview with Clinton Rubin came out last week, I think, and then the doctor, convinceder from power plate came out this week. I have my conclusion. Video is actually set to come out today. I delayed it because I I've sent
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Dr Doug: Dr. Ruben a couple of studies. I found that
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Dr Doug: I wish I'd have I interviewed him. But basically showing that the devices
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Dr Doug: at the rate that they
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Dr Doug: set their stand. Their their settings aren't very effective. And so I I sent him those, and he sent me some stuff back, so I haven't reviewed those yet. So I put that video on pause cause basically in that video, I say, I don't say it directly. But I kinda say, the research doesn't really support the the less than one G force devices. We should really be looking at the the more powerful devices like power plate.
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Dr Doug: So II think I'm still going to think that I but I wanna review that before I put that video out. So I don't have to retract that statement but in the meantime we have set up a really strong affiliate relationship with power plate. So if anybody's thinking about getting a power plate there is a link. I can drop this.
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Dr Doug: I can do this smart enough. I can drop this in here, and then you'll also get an email about it. But I'll drop this in the chat just in case anybody is thinking about it. And I think right now, actually, they're having a sale, anyway.
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Dr Doug: And I think this link will actually go above and beyond that their sale link. But just if anybody's thinking about that, I like the power plate devices. I think the question comes down to whether or not you can tolerate them. And so they're actually sending me one to do some videos on and my wife is one of those people that doesn't tolerate them very well. So I'm gonna see how she does on like the low settings of the power plate.
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Dr Doug: such a controversial topic. It's funny.
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Dr Doug: So we'll come to a conclusion on that. But I wanted you guys to see that cheryl asked in the chat. So do you think power plate is safe for people with low Bmd, and how low? Like negative, 4 low. Yeah, sure. Let's low. So if you have a T score of negative 4, I still don't think the power plates gonna break a bone.
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Dr Doug: You know the amount of force that you're getting through your spine by the time that the the force goes through your body goes through your legs, especially if you bend your knees a little bit. You're really not getting. And and there's there's no way to accurately measure this. But you're not getting the whatever 3 to 5G's that you're getting at your feet. You're not getting that in your spine. And so you could start on the low setting.
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Dr Doug: You could also put, you know, one leg on there. You could put half your body on there. But it makes sense to me that you would need more force to go through your body rather than what the meridian does. So I do think it's probably safe from a bone perspective. The question I have is, what about somebody that has inner ear issues?
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Dr Doug: What about somebody that has you know, like my wife, for example, like she gets really she gets a lot of like
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Dr Doug: nausea, and like uneasy feeling in her head. If she's on a vibration plate. I don't know that the cornea separation thing or the retinal se retinal detachment rather is an issue for short term use. I think that's more of an issue for long term use. You know, if you're like, in a
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Dr Doug: whatever you sit in a machine that vibrates all day long.
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Dr Doug: So that kind of thing. Does that make sense any questions on vibration devices? I can answer. Since I've I'm very steeped in the research right now.
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Cathy H - AZ: Yes, I ours is called Vmax Pulsar.
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Cathy H - AZ: and it, you know, it does the both things, one that just vibrates in the one that bounces you up and down. Which are they calling? Which I'm really unclear?
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Dr Doug: Yeah, it's it is really hard to to understand the terminology. So there's there's basically how to describe this. There's like 2 main ways that they create vibration. One is sort of a teeter totter
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Dr Doug: right? So there's like a fulcrum in the middle. And the things going do do do those generate potentially a lot of force?
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Dr Doug: The power plate uses a 3 dimensional kind of
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Dr Doug: rotating vibration. It doesn't feel like it's doing this, but this is what it's doing underneath you. And I think that gives you a more even amount of up and down. So the whole plates moving up and down at the same time rather than the back and forth because the back and forth, depending on where you're standing is gonna change the force that you're seeing dramatically. And there's there's no way for, you know a machine to know what that is. So that this this I think that most of the cheaper devices
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Dr Doug: are going to be the teeter totter because they're easier to build. That doesn't mean that they don't work.
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Dr Doug: I just there. There's isn't as much research with them. So I have. I've had a lot of comments on Youtube, of people asking for a less expensive device. And II just don't know. I don't know of one that is as good a quality as what powerplate does. I know they're expensive. They are really expensive. So I just, I'm concerned about the teeter totter design. And then also just from a durability perspective. But I hear some of them come with great warranties, too.
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Cathy H - AZ: Yeah. So this one, if you kept it on like real low, like one or 2, and you're doing a little Ti mean, I've just been doing. I was believing the maradine, so I was just doing the vibration.
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Cathy H - AZ: And now I'm hearing that's not enough from you. So the teeter just a little bit of the teeter taught it with the vibration. Maybe's okay.
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Dr Doug: Maybe it's hard to know right? And and that's the that's the unknown. And that's why I'm I'm hesitant to recommend any of the other devices, because they just haven't been researched. Power plates been all over the place.
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Dr Doug: so I'm comfortable with that style. My wife and her. Her clinics uses a teeter tower device, and
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Dr Doug: you know I don't know how many people been on them for how many minutes, but we haven't seen any issues so probably safe. But
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Dr Doug: but I can't say that for sure. Okay, thank you. Yeah, David.
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David Callen: So if you're looking at to having to spend your time using a vibration machine versus, and I'm also working out I'm I'm hearing you say.
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David Callen: correct me if I'm wrong, that probably your workouts probably the more important.
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Dr Doug: If you were to pick between the 2, then I would pick resistance training over vibration. Yes, however, the vibration only takes 10 min. So you're not going to get a workout in 10 min so you could vibrate on days. You don't have enough time to work out. You'd also vibrate, I mean, there's
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Dr Doug: if you can't find 10 min in your day, you might need to reevaluate your
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Dr Doug: your time priorities.
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Dr Doug: so I think that there's an easy way to get 10 min, and in addition to a workout, I think the biggest issue is, do you have the resources to get to get a plate? And it, you know, does that make sense, add onto the stack, and I think that it does.
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Dr Doug: But it is just one more thing. You know, I discovered that my physical therapist has a plate which means
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David Callen: insurance pays for.
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David Callen: Well, that's that's great.
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Dr Doug: You gotta get there. But still, yes, we'll we'll dedicate anything that insurance will pay for except for drugs.
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Xanet (Jenay): we will consider. Yes. Janet. Yeah. So just I had quite a bit of experience with the power plate at my osteogenic loading place
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Xanet (Jenay): and initially, when I got on it was like maybe super nauseous, and the vibrations went to my head. It took me almost a year, but I eventually was able to have both feet on kind of at the same time. And so there are ways to like build up your ability to be able to handle it. I don't know. During that period of time it was helpful. But we would do it like one leg at the time and one leg on the floor, and there's pads. You can put over it as well. That
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Xanet (Jenay): holds the vibration down so it is possible. I guess I would say, and that's what Mike Lewin, of strength. X here in Ashville or Black Mountain? Oh, yeah, so exactly. So. He yeah, he does that exact same thing right? So he has the. He has the cushion. You knew 1 one leg at a time. Yeah. And so he'll work people up to the point where they're standing on it. I actually, I think he told me about you, but didn't use your name.
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Dr Doug: Good! Well, I'm glad you got there? And then, sarah asked a question about just the metrics of G forces compared to Hertz.
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Dr Doug: There's so many numbers when you look at these studies. It is really confusing, and physics is. I love physics, but it's certainly not my my strong suit. So the when they talk about Hertz. That's the frequency of the device. So actually, power plate on a low setting. And the maradine have the same frequency.
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Dr Doug: It's the amount of displacement that's different, and the way that they do it. But the amount of displacement, meaning the amount that the the little plate goes up and down and that the amount of displacement is what's really different. So the meridian and the video, I said, this is between 50 and 200
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Dr Doug: micrometers. I think that's the right measure of unit, and there's a thousand of those in a millimeter. Right? And then there are so the displacement of the power play is about 2
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Dr Doug: And so it's
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Dr Doug: if, whatever the multiple is, it's a whole lot more. I'll put it that way right? So the amount that the Powerpoint is moving is substantially more than the amount that the meridian is moving. And that creates different amounts of Gs or G forces. So the meridian, they will say it's between
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Dr Doug: what do they say? Point 8 or point 4, I think point 4 point 4G's. And the the power plate is around 3 G's. One of the studies that that Ruben sent me actually.
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Dr Doug: as a as a counterpoint is that they, when they, when they were measured outside of the powerplate environment that they measured it more like 10 Gs. So I sent that over to the CEO of power plate, and I haven't heard back from him yet, so I think it's supposed to be around 3 to 5G's. And that's what the research supporting those devices would say so.
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Dr Doug: That's what all that means.
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Dr Doug: Sure, Cheryl says I'm on a meridian now. Great! Where are you, Cheryl?
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Cathy H - AZ: Yeah, 1 one more quickie question. So I'm trying to lift my weights and stuff while I'm standing on it. Is there a benefit to that?
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Dr Doug: So some of the research they they did exercises on it. II don't think that the I don't think that the bone benefits are better necessarily. Although, Janet Mike does exercises on it right?
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Dr Doug: Yeah. So II don't know if it's just from a convenience perspective. I mean, obviously, you're saving time, right? You're doing 10 min of resistance training while standing on the on the unit. Th. There are some studies that did do that.
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Dr Doug: but there are not well enough controlled and comparable studies to know that the resistance training was actually better than just standing on the machine alone.
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Dr Doug: Okay.
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Dr Doug: alright.
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Dr Doug: So let's dig into some of these other things. Some big topics here. I always like to talk about hormone topics first. I've just been in such a hormone.
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Dr Doug: such a love of hormone research lately.
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Dr Doug: let's talk about men since since David's here. My, my, my one guy thanks, David, for showing up. I appreciate a little manpower.
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Dr Doug: So this is a question from Greg. Greg asked, when taking testosterone by injection, what blood love blood levels easier for me to say, should we expect to be normal also? What is considered the half life of the injection. 2 great 2 great questions. And this is valid for both women and men. So pay attention. Everybody. So normal testosterone levels are not normal.
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So testosterone levels when you look at lab, core or quest, and they're both different.
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Dr Doug: The the reference range is either one of 2 things. It's either completely arbitrary or it's a statistical average of the population. Both men and women have had declining testosterone over the last several decades. So if a statistical average is not normal. If it's arbitrary, it was probably chosen by somebody who doesn't know anything about testosterone, and that's probably not good either. So normal. You have to talk to somebody who knows what they're talking about.
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Dr Doug: So
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Dr Doug: my camera just did something weird. We'll see what happens.
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Dr Doug: That was apparently a signal for it to do something.
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Dr Doug: It's still on. Okay. Good. So oh, that was to go to whiteboard mode. I don't even know what that is
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Dr Doug: okay. So for men, we look at total testosterone. But we also look at other factors. So for men, we're kind of aiming arbitrarily between 800 1,200 total testosterone. But we see. And this is really important for women, too. We see that depending on the sex hormone binding globulin. SH. Bg, that that total testosterone could actually be great when you look at free testosterone, or it could be not enough.
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Dr Doug: The Shbg binds on to testosterone. And so if you have a high SHBG. Which is mostly genetically driven, if you have a high SHBG. Then even a testosterone of 1,000 might be insufficient.
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Dr Doug: So we just had a guy yesterday
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Dr Doug: he had a testoster10, my gosh! What was it? It was like 800 or something, but his free testosterone was still like in the single digits, in like low single digits, like postmenopausal women, single digits, and it just blew his mind because he was like, I've been to the doctor so many times. I have all these symptoms of low testosterone, and nobody will treat it
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Dr Doug: right, because they only check your total and your total looks amazing for your age. But you don't have any free testosterone. So there's some ways to to to deal with that. But ultimately we'll probably end up replacing that. The other question is, what's the half life of the injection? And, Greg? It depends on what type of testosterone the vast majority of practitioners will use testosterone sippine. 8. What I use for both men and women when you do an injection, the half life is.
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Dr Doug: I think it's like a day and a half something like that. That's why we do twice weekly injections. So we'll inject like Monday, Thursday, or some some schedule like that, so that you can keep relatively consistent.
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Dr Doug: Some people have gone to everyday injections. That's a lot of intramuscular injections for my taste. You can also switch to sub queue. But people that get issues with sub queue injection. Because the oil is really made for IM application, not sub queue. So there's some different ways to play with that
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Dr Doug: from a woman's perspective. This is really important, because we now have, because we have so many women on testosterone.
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Dr Doug: women will come back with their labs. We get this all the time they'll write in. Oh, my God, my testosterone is so high
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Dr Doug: total testosterone, you know, 80 to a hundred, which is high. But these women also have high Shpg, and they have low, free testosterone, and they still have symptoms.
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Dr Doug: And so the the reference range for testosterone for women is, is much much lower than that. But yet we should be treating to symptoms, not to lab ranges. So as long as they're not having side effects we'll keep tight trading up until we get to resolution of symptoms. And that for for some women is is over a hundred, and which used to make me nervous, but not so much anymore.
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Dr Doug: alright! Any questions on that
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Dr Doug: no great? Oh! David asked, so do you take these shots for the rest of your life? Great question, David. So the short answer is, yes, you can come off of it.
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Dr Doug: But my question is, if you had low testosterone, why would you ever want to?
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Dr Doug: You can reboot the system. I can't guarantee you what your performance would be like with the system rebooted versus on replacement. But if you had low T in the beginning, you're gonna have low. T again. It's not gonna get better. So generally I tell people to be committed to, to to take it for the rest of their life. Same with women.
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Dr Doug: Speaking of women.
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Dr Doug: there's a question here from Thomas about high Psa, and and prostate and testosterone. The short answer to that is Thomas, is that the the prostate has a saturation of testosterone at a very, very low level. So unless your levels are like below, 200 like super low. Then you're unlikely to have any impact on Vph when you replace testosterone cause. It's already been saturated. As far as your prostate knows, there's no additional testosterone.
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Dr Doug: Okay, women's hormones. Yes, ma'am. Who is that? Oh, sure.
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Sheryl: The testosterone.
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Sheryl: test that I was. II got before I started on Hrt, had a total and free, direct
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Sheryl: and
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Sheryl: and you're saying that it doesn't really matter what the levels are has to do with your do your symptoms
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Dr Doug: like, is there not not a goal? So we we use both. I'm not quite comfortable just going off as symptoms, because we don't, especially with testosterone. We don't know exactly which symptoms we're aiming for. I was just at a conference this weekend with Gabriel Lion. She had her first forever strong conference, which was super fun, and she had a panel of of people, including Mary Claire, if you guys know who that is. She's a big menopause advocate, overgoyn huge
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Dr Doug: huge following on Instagram. She's good to follow.
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Dr Doug: But her and another kind of men's directed testosterone expert were talking about this, and that's how they practice both of them. We don't even measure. We just go based off of symptoms. I'm not quite comfortable with that cause. I don't wanna drive a woman to have a very high testosterone high dh, and then have some funky side effects like that's just not not how I practice so I would still look at the total and look at the free. But then ask you about your symptoms, and then we can come to a conclusion there.
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Dr Doug: that makes sense.
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Sheryl: Okay, yeah. Sh vg, was high before I started, and I wasn't able to do testosterone. So
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Sheryl: I just retested, and of course the sh Pg. Has gone up. Is there a concern with
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Dr Doug: Hi? SH. Bg, other than it? So it's it's associated with things, but not
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Dr Doug: not strongly. And and it's not. It doesn't cause anything. It's just what your body your body's just making protein to carry around hormones.
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Dr Doug: And there's really not a lot you can do about it. Some people will try to manipulate Shpg with dietary patterns, but I've never seen anything to be effective.
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Sheryl: Thanks.
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Dr Doug: Yeah.
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Dr Doug: Sarah asked. Real quick about oxytocin. Is oral versus nasal spray. Better from a viability perspective. I've not seen any studies on oral, so I don't know the answer to that. I've only seen it for given in nasal spray, so I would assume that it's probably going to work better that way. If you think about where you want it to work, you want it to work in your brain. And the easiest way to get to your brain is actually through your crib form plate in your nose.
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Dr Doug: And then.
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Dr Doug: Janet asks, what's the relationship between estrogen and histamine intolerance? That's a really interesting question.
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Dr Doug: So I think, as estrogen drops, you become more histamine intolerant. And I was just listening to.
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Dr Doug: Do you guys know Stacey Sims?
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Dr Doug: So Stacey Sims is an author. This is her first book. She has a follow up book called Level Up, next Level, next something. Where is it?
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Dr Doug: Somewhere? but it's basically her performance book for women
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Dr Doug: in the post menopausal phase. So she actually talks quite a bit about this and so it seems like as estrogen drops. Histamine tolerance goes up
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Dr Doug: which is weird. So many things happen when extra check goes away. let's talk about alright. So women's hrt So Sarah's asking if you take aromatase inhibitors as an estrogen blocker, would the aromatase inhibitor also negate any benefits of testosterone supplementation? No.
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Dr Doug: this is something we're playing with for women that either aren't allowed to or refuse to take after gym.
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Dr Doug: so you can give testosterone and give aromatase inhibitors which block the conversion of estrogen to testosterone and then still get the benefits of testosterone, which are, gonna be all the things that are that are known with testosterone, except for the ones that come from the the trans transfer of estrogen.
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Dr Doug: So you still get a lot of benefit of testosterone with an AI, and that's something that we've started doing actually with patients. The alternative to that is to use drugs like Relaxophen. But we've had some patients not have good side effects as a result of those drugs. So we don't do that anymore.
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Dr Doug: Meredith asks.
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Dr Doug: what levels of the various hormones should we be aiming for when undergoing. Hrt. If cycles have resumed during HRT. Would this, then, complicate the levels? So let me just start there. So for Emredith, are you here? No, no, no, no, okay. So
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Dr Doug: if a woman is in the kind of perimenopausal state where she still has cycles, but maybe they're inconsistent. And she starts estrogen. If her cycles return, then yeah, that gets a little wonky. Right? So what's happening is, the ovaries are sort of, you know. They're like an engine running out of gas. Right? It's like then off and then and then off. And that's why symptoms can be terrible.
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Dr Doug: So I hear so I would actually back off of estrogen, or at least use a very low dose, because you're gonna be essentially adding fuel to the fire of the up and down.
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Dr Doug: Once the cycles have stopped. Then we're aiming from an estrogen perspective around 40. I think it's remember the units but on lab cores between kind of 40 and 80 is the range we're looking for. Not physiologic. And there are some protocols out there like the Wiley protocol, is something that people may have heard of. Where the the attempt is to use high levels of estrogen and progesterone to actually recreate menstrual cycles.
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Dr Doug: I don't know why anybody would want to do that, but it's out there, and I don't know what the risk profile of that is. So we don't do that.
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Dr Doug: She goes on, and then ask,
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Dr Doug: does a short cycle indicate? Progesterone levels are too low? Not necessarily
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Dr Doug: She is on a bi-identical with a biased 50 50
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Dr Doug: cream and testosterone, plus a micronized progesterone. So and that's okay. I've I've shifted away from biased as well. So for those aren't familiar. Estrogen creams kind of come in 2 forms. There's Estradiol alone, and then biased versus Estradiol and Estriol
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Dr Doug: Estriol. II don't know the origin of this move. I think this happened kind of in the functional medicine space where people were looking for a quote unquote, safer solution.
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Dr Doug: and estriol is safer than astral dial, mostly because it hasn't been studied as much. But if you think about Estri Estriol from a a functional perspective, Estriol
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Dr Doug: is only really present in high amounts during pregnancy.
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Dr Doug: And so we don't really like we. It doesn't do much in the body, otherwise it's not very. It's not a very strong agonist for the estrogen receptor. So really, the estriol is getting in the way, and it's not letting extra dial do what it's supposed to do. So we pulled everybody off of bias, or at least we're in the process of that and putting people on astronle alone, so that we're just using the one that we want to actually use and then otherwise it's a matter of looking at symptoms. And then dialing in dose both with symptoms again and with
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Dr Doug: lab values.
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Dr Doug: Caitlin asks.
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Dr Doug: why is cyclic progesterone and estrogen better for bone health if both of these hormones promote osteoblast development? Oh, good question
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Dr Doug: wouldn't constant exposure via oral contraceptives. Therefore be a good thing. So 2 big components there, Kaylin, so number one is the cyclic progesterone and estrogen
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Dr Doug: is important when a woman still has cycles because they counteract each other, so Progesterone is osteoblast promoting the estrogen is osteoclast inhibiting.
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Dr Doug: so you could say that they're both on the same side of that metabolic thing, but they do it in different ways. So you want Progesterone to boost osteoclast function on one side, and that's when it goes up and it comes down, and then estrogen will come up and block osteoclast. And so you're getting you're still manipulating it from one side. But you're still getting the C saw back and forth.
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Dr Doug: Does that make sense? So? Oh, my camera is doing something again. I gotta turn these things off. So you're still getting that C saw back and forth every month. That's why Amen are such a big deal. For women. If you run into a man area. You will
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Dr Doug: likely have lower bone density issues. Sorry gotta turn all these things off.
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Dr Doug: I don't know why my camera decide to be. Fancy.
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Dr Doug: There we go! Pop it.
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Dr Doug: stop it! There we go. Okay.
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Dr Doug: oh, and then hormone hormone replacement through contraceptives is not a good thing, because, first of all.
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Dr Doug: you don't get the cyclic back and forth. Secondly, all contraceptives are using proges, not progesterone
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Dr Doug: so progestins or synthetic progesterones developed in the 1950 s. They are the causative agent. That look that caused the increased risk of breast cancer in the Women's Health Initiative. They will cause an increased risk of breast cancer, blood, clot, low bone, mass mood changes.
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Dr Doug: probably something else that I'm forgetting. But progestins should not be used by anybody under any circumstances. In my opinion.
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Dr Doug: Why would you? You have Progesterone? Use the thing that works
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Dr Doug: that's safe. Oh, Julia's here.
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Dr Doug: Hi, Julia! So Julia is one of our coaches
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Dr Doug: who just popped on to learn more about what we talk about.
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Julia Priest: I assume. Hey? Y'all good to see ya
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Dr Doug: all right. And then last hormone question, oh, there's 2 more. Ok, next hormone question regarding Hrt. Karen asks.
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Dr Doug: she's gonna start estrogenic Progesterone Bio identical. But number one. What do you think of just the estrogen ring alone? And if I go with estrogen and Progesterone is the patch. Okay? And pill for Progesterone? So let me just start there.
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Dr Doug: So the estrogen ring is going to only provide a local administration in the vagina is my understanding. I'm not an obgyn but I don't think you're going to get systemic release that way.
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Dr Doug: The estrogen and progesterone you do want to pair those 2 together. Of course, I would also say testosterone for most women, assuming that you need it.
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Dr Doug: but an astra dial patch is okay. The dosing is not always great, and it's hard to test
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Dr Doug: most ovas won't test your levels if you're using an estro dial patch. But you can get adequate levels of estradial with a patch and then a micronized progesterone capsule in addition. Yes, don't let them put a progestin and a patch with the extra dial and give it to you that way, cause that is also available. And then you're getting that project in
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Dr Doug: I mentioned in my class that estrogen cream progesterone and testosterone cream. Can you enlighten me? What is the estrogen cream you're referring to? And of course,
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Dr Doug: what's your take on the ring? Yeah. So the estrogen cream is astronle, and then testosterone cream can be combined into that. We start them separately, and then we combine them later. Once we get the dosing dialed in
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Dr Doug: so Cheryl is educating me that there are 2 rings, one local and one supposedly systemic. Cheryl, do you know, is that still vaginally applied, I would assume
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Dr Doug: we'll let our answer that. Oh, yes.
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Dr Doug: So I know that it's possible we've had women who've used vaginal Estradiol creams with the goal of achieving systemic levels. So I know it's possible to do it through the vaginal mecosa. Yeah, femur
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Dr Doug: I've not seen femme studies showing what levels it actually gets to, and that would be my concern. Because when I've had women try to use compounded creams for that purpose, they can't get enough cream in there, and it's kind of a sloppy, goopy disaster. The femme obviously wouldn't be that but my question would be, can you actually get high enough levels. It might alleviate symptoms of menopause. But is it actually gonna achieve levels of estrogen for bone, brain and heart elf
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Dr Doug: be my concern?
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Dr Doug: Okay? And then adverse effects. And Hrt, these are always fun. So can you tell us whether the benefits of Hrt can be realized if someone is 20 years out from menopause. Great question.
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Dr Doug: so let me just start there. So when someone's 20 years out from menopause, we see this quite a bit that 10 to 20 year
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Dr Doug: age group is right when the Women's Health Initiative came out. Right? So there's an entire decade or 2, almost really an entire generation of women that got the shorthand of hormone replacement because all the doctors were scared away because of the Women's health Initiative and other studies.
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Dr Doug: So now we're forced to ask this question of Can we use it for women that are 1520 years out? And the short answer is.
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Dr Doug: Yes, but the risk goes up, and the risk is going to be variable from person to person. And so the risk that we're concerned about here is the risk of cardiovascular disease, not the risk of breast cancer. For most people
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Dr Doug: the risk of cardiovascular disease goes up because once you remove estrogen from the body, your arteries get harder.
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Dr Doug: There's more chance for those arteries than to get dysfunctional and develop plaque. And then if you add estrogen back and you loosen those things up, you could potentially break off a chunk of plaque, and you do see a signal for that.
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Dr Doug: So what we do is we look at some of these risk factors. What has their cholesterol been? What is their family history? Do they have any imaging of their heart? And if they don't, let's get some, and let's see what your disease looks like. If you've got clean looking pipes.
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Dr Doug: and you have severe osteoporosis, it probably makes sense to treat the thing that we know and not be worried about the thing that we are worried about.
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Dr Doug: I can't say that that wouldn't potentially cause an event.
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Dr Doug: But I'm if I'm worried about you breaking your hip versus having a heart attack with clean arteries.
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Dr Doug: I'd probably rather put you on Estrada
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Dr Doug: even if we can't, then we would potentially use progesterone and testosterone because they're not gonna have that same impact and still benefit somebody. So those are kind of our 2 plays there.
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Dr Doug: I talked about the Progesterone already.
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Dr Doug: and I just talked about that great
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Dr Doug: alright. And then last hormone question.
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Dr Doug: I don't know how to say this, Oranka aranta
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Dr Doug: she says it's my understanding that the risk of stroke is higher in Hrt. Than in Bisphosphonates. even evinity. And Forteo.
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Dr Doug: however, you do use Hr. T. Much more frequently than other types of medication. What are the advantages and real risks I like how you said that. Also, I don't find any research about the benefits of bio identical hormone supplementation versus traditional
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Dr Doug: treatments. Are there any proven advantages? And those are all great questions.
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So let's deal with this first one. So the risk of stroke is higher in Hrt. Than in bisphosphonates affinity or forteo
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Dr Doug: so I think what she's getting at here is she's saying that we're exposing people to a higher risk of stroke with Hrt. Rather than with the bone. Health drugs. And indeed, there is not a high risk of stroke in the bone. Health drugs. So if there's any signal for increase in stroke with Hrt, then yes, it would be higher. But we're treating different things and for different purposes. So we're treating people with Hrt for all the things that come along with aging in addition to bone health.
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Dr Doug: whereas the Bisphosphonates, affinity and Forteo are short lived only gonna impact bone and have potential negatives. So they have other side effects. So that's the trade off. I'm not just looking at one side effect from one to the other. Is there actually an increased risk of stroke? Not if you use estrogen topically
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Dr Doug: testosterone topically, and micronized progesterone. Orally, I don't believe that there is actually an increased risk of stroke.
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It's here
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we use HIT much more frequently than other types of medication. True.
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Dr Doug: And then is there an advantage of bioidentical hormone supplementation versus traditional.
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Dr Doug: And what we have to look at here is that there we are. Only we have to use the commercial
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Dr Doug: driven research to understand what's happening with the the biodenical hormones.
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Dr Doug: Now, fortunately.
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Dr Doug: we actually do have commercial research on this to to leverage. So Estradiol is used in
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Dr Doug: most studies. And you can even leverage what the Women's Health Initiative used, which is primaran, which it was mostly estr dial to understand what those risks are. So when we're talking about bio identical extra dial, it's the same that's in the patch. It's almost the same that was in premarin and the Women's health initiative. So I think it's safe to say that those things are all the same. The route is different. Primarents, oral patches, or patches and creams, or creams, both going through the skin.
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Dr Doug: and then micronized progesterone, as
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Dr Doug: Prometrium is also a commercially studied product that has FDA approval. So we know what the the risks of that are. And then, testosterone. There are a lot of studies. And I'm I'm actually writing a book on testosterone and women right now. So I can tell you. There are a lot of studies. They are mostly driven around sexual function, not around other advantages of testosterone, but
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Dr Doug: none of the studies show any concerns other than the potential androgenic risks. So I think I'm comfortable using those things for those reasons.
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Dr Doug: Alright. Any other hormone questions before we move on.
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Dr Doug: So great. All right, let's
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Dr Doug: Let's we guys want to talk about supplements
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Dr Doug: and a lot of supplement questions, or exercise your choice supplements, exercise somebody, throw it in the chat
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Dr Doug: supplements. Alright, Alan.
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Dr Doug: let's talk supplement.
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Shelly’s iPad: Here's a good question that would. You can decide what's more important, supplements are exercise.
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Dr Doug: Well, II would say, exercise of of the 2, if you're gonna pick one. But the good news is you don't have to pick one.
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Dr Doug: So alright. Let's talk supplements here.
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Dr Doug: Oh, yeah. So this this came from
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Dr Doug: Dell actually
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Dr Doug: thought that was for a short for my my name, anyway. Those are also my initials. But Dell asks about this new calcium collagen product called coact. It's KOAC. T.
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Dr Doug: And I've seen this before I went to their website. And they have. They have the results of a study, but they don't actually cite the study, which is always annoying to me.
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Dr Doug: It sounds cool, but I haven't read the study, so I put this on my list to talk to my team about I'll have my my PA or Npa take a look and see if we can find the actual studies on it. They claim a 9% increase in bone minor density. With this over a calcium alone group. My concern with that claim is that if you're just giving somebody calcium.
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Dr Doug: that's probably a bad idea. But secondly, you're basically looking at the decline of bone health compared with maybe maintaining, and that you could actually achieve a 9% difference between those 2. So we'll see more to come on that. I have that on my list of things to research. So coact coming, it's on a bunch of different products.
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Dr Doug: Jennifer asks. She has severe osteoporosis and celiac disease. Her doctor wants her to give herself a shot every 2 days. So that'd be for Teo or Timlos.
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Dr Doug: I want to try. She wants to try our recommendations first. Great congratulations.
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Dr Doug: I had a back surgery to cement 3 fractured vertebrae in October. Pouch fractures happened from horseback riding. Oh, a horse bucketing. I didn't go off okay.
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Dr Doug: but rode through it. She's 70 years old and done riding horses. That's sad. Should she start? Osteoprev is what she's asking, so I can't give specific recommendations. But here's the recommendations that we do for for calcium for patients, which is, we have patients track their calcium chronometer or chronometer, depending on how you say it is a
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Dr Doug: a free app. We use a pro version in the practice, but it's a free app. You can track all your food, and you can see how much calcium you're getting through diet.
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Dr Doug: If you're getting 1,200 milligrams of calcium through diet, you don't need a calcium supplement. I think you should probably still have a micronutrient supplement, you know, like a central minerals trace minerals. But you don't need a calcium supplement. So osteop I like, because Osteop doesn't have a lot of calcium in it, and it has a lot of other stuff in it. So it is a cool product. We do use that. I've also been back to using alga Cal.
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Dr Doug: And the reason why is because
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Dr Doug: I've been. I had this conversation with the CEO of Algae Cal, a few weeks ago, and and he fed me a lot of data on why, they're using what they're using with the idea that algae is a whole food source of calcium.
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Dr Doug: and that whole food sources of calcium do not bear the same risks as calcium supplementation. So we're definitely in a gray area with that, because ground up bones are also whole food sources.
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Dr Doug: maybe, you know. But is algae? Once you dry it and put in a capsule, is that still a whole food source? So I don't know. I think that both of those are better than, say, calcium carbonate, which is literally ground up rock.
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Dr Doug: so I'm sort of in a discovery phase with that and with them but either one of those 2, I think, is good. If you need calcium. Those would be my preferences. probiotic question.
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Dr Doug: So there, yeah, there was a study II heard about but did not read this study. The potential of probiotics is therapy prostate process. When we did our our gut health module we found a couple of studies like this.
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Dr Doug: The thing about all of the studies on on the microbiome is that we don't really
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Dr Doug: know the difference between association and
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Dr Doug: intervention. Right? So like I was just, I'm recording with my wife this afternoon a
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Dr Doug: kind of a rebuttal to the the Netflix movie, the twin study
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Dr Doug: all about eating plant-based diet. And so
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Dr Doug: they talk about this in there, too, and it's like when you look at the microbiome of somebody who has a desired health state, whether it be healthy or lean or muscular, or absent of a particular disease, or with a particular disease.
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Dr Doug: You can see a trend in their microbiome.
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Dr Doug: but there's no evidence to say that giving a probiotic, or, you know, any kind of manipulation of the microbiome will actually change the disease state. So I think it's a question of, you know, like the tail wagging the dog right? So I think the the microbiome is demonstrative of what's happening in the host
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Dr Doug: be in the human.
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Dr Doug: But I don't think we can manipulate the microbiome to change the host. Now the research behind what's it called? Oh, fecal transplant
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Dr Doug: sounds like a superfine procedure. The evidence behind fecal transplant would show that that is potentially true. But you're changing the entire microbiome with another microbiome, and that is not the same thing as taking A supplement.
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Dr Doug: So for me, I recommend probiotics. I don't really know that they're doing much other than repopulating for people that have had. You know, dysfunctional microbiome that we, you know, decimated with antibiotics or or natural antibiotics. So I don't know. I don't think that we're gonna reverse osteoprosis. I think we're just seeing a a consistent state of people that have dysfunctional microbiome with osteoprosis. But I don't know that we know what that means.
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Dr Doug: That makes sense.
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Dr Doug: Candy had a follow up question around Lorna. Thank you, Lorna. You've been paying attention. Candy. And Lorna had a follow up question about calcium. Lorna is is calling me on being inconsistent with my milligrams of calcium so I've been. I've said in the past. If you have, if you consume over 800 milligrams of calcium through diet. Then you don't need to supplement. I just said 1,200.
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Dr Doug: And, Lorna, I'm not. I'm not going back on that I think 800 is enough.
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Dr Doug: because most countries it is 800. But when it comes from calcium, from whole food sources, and this is where this gets so tricky.
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Dr Doug: like. One of the reasons why I stopped using algae cal is because it has 720 milligrams of calcium. If that were coming from calcium carbonate. I think that would be too much for almost everybody.
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Dr Doug: but it's coming from a whole food source. If someone wanted to drink 3 cups of raw milk a day, and they were getting.
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Dr Doug: you know, 600 milligrams of calcium. But I tell them it's too much calcium. I wouldn't.
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Dr Doug: So
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Dr Doug: I think there's just there's probably a big range, and as long as you're getting it from whole food sources, you're getting it with vitamin d. And Vitamin KI don't know that we need to be that nitpicky.
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Dr Doug: but if you're getting 800, do you need to add another 800? Probably not, you know. Then I would just focus on the other micronutrients. and then Candi also asks if we get enough calcium through food. It would be beneficial to take the second tab from Algacel with strontium.
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Dr Doug: Yeah, I mean strontium for me. II think that there's value.
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Dr Doug: How much is it going to impact our bones. It's going to impact our dexa. We don't really know how much it impacts bone strength.
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Dr Doug: And so this is where for people that have really low T. Scores. I'm totally fine with using it. I think it can help both mentally to see your T. Scores come up and Bmd. Come up.
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Dr Doug: but I wouldn't push into it if we don't. You know, if you're not in that group, if you have relatively mild osteoprocess, I wouldn't take strontium. I don't think there's any risk I think we just run into. You know, we run into financial and capsule fatigue challenges.
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Dr Doug: Sharerall asked a great question about the Gi effects. Does no growth mean deficient or just inconclusive? Lab?
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Dr Doug: I have to look at have to look at those results. Cheryl. No growth generally means no growth, as in that. That bacteria is not growing.
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Dr Doug: And candy said, negative 4.1. Yes, the candy that's low. So yeah, candy. If you were my patient I would have you on strontium.
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Dr Doug: You're welcome. Okay, so let's move on
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Dr Doug: a lot of calcium questions.
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Dr Doug: Okay, Debbie asked about getting conflicting advice about how much calcium to take. She had bariatric surgery 9 years ago, and as a result have malabsorption.
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Dr Doug: She was recently diagnosed with osteoporosis, which is super common after bariatric surgery.
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My recent lab showed vitamin D was low at oh.
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Dr Doug: was low, normal of 30. It was 15. Well.
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Dr Doug: that's better. My Doc told me you have to go on prolia
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Dr Doug: So, Debbie, I can't tell you it really is right for you, because I need to know a whole lot more information. However. The amount of calcium that you have to take to get absorption through your gut is going to be really tough to know. Unfortunately.
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Dr Doug: You know, we could do what I would recommend doing actually is and we're playing with this. I have it sitting right here beside me is doing a HTML here tissue mineral analysis, or using a a tool like neutral eval to look at byproducts of
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Dr Doug: of calcium absorption. I'm pretty sure neuter eval does it? I know HTML does it, and the reason for that is that I don't think there's any way for you to know if you're getting enough calcium, or if you need to take big doses of calcium, or is that gonna hurt you? There's no way to know other than knowing what's happening in your blood and in your body. So I would try to use one of those 2 tests. To see if you actually need more calcium. It's a little hard to know, too, you know. Which portion did they remove, and how much calcium you're getting absorbed? It's so tough
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Dr Doug: so a tough position to be on as far as having to go on pro laya. We just need more information for sure. Thank you.
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Dr Doug: Oh, Hi, Debbie, yeah, you're welcome.
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Dr Doug: So the the Karen asked about algae Cal. I think we just covered that. Their omega 3 fish oil. It's a good quality of fish oil. The challenge I have for patients with a liquid based fish oil is whether or not they can tolerate it. They? They say in the ads that it tastes great. I've never tasted it, but I've also never tasted the fish oil. It tastes great. So
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Dr Doug: see
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Dr Doug: see what you think. It's a good quality one, but there's lots of good quality ones.
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Dr Doug: And Susan was asking, I guess, actually right right about Aljakal. She said that she emailed the admin of Algae Cal. It read the Consumer lab. So they were slightly elevated. Lead, content, and she's been taking the garden of Life, vitamin code, rock house on the top of the price.
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Dr Doug: and they say that it's sourced from the same place. Yeah. So I think it just depends on
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Dr Doug: it depends on who you want to commit your dollars and faith to the thing about, you know, saying that there's elevated lead content. You gotta remember that these things are naturally occurring like lead is naturally occurring in the environment. So if you pick up algae, and this is my concern about algae is that you're gonna get whatever's in the environment.
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Dr Doug: You're gonna get some of that same thing, though, like with the with the ground up bones like, what have those cows been exposed to? That's in their bones? You know we don't. It's it's really hard to have a perfectly clean life as a cow. So there's probably stuff in those bones that we
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User: that we're gonna end up getting through a supplement that's that's made from ground up bones. So I think we're always gonna have some contaminants. So I think you have to trust the company. Now.
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Dr Doug: Garden of life, you know. Have they done the same testing? If it's coming from the same source, I would assume that it probably has some of the same contaminants. Right? And so I think it just depends on who you want to commit your your faith and your dollars to. I try to
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Dr Doug: use the best products that I can for myself, and if you trust garden of life, then use garden of life. You know half the price sounds great. I would also look at the other components, though, and are they of high
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Dr Doug: quality? And so that's there's so many things that go into a supplement and definitely considered making our own, but it is
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Dr Doug: not easy to do.
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Dr Doug: I'll let that go
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Dr Doug: alright. Some d 2 sorry vitamin DK. 2. Hopefully. Not d 2
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Dr Doug: questions. So let's talk about this. So Kim asked. Oh, and Diane, I see you added some information. Here, let me just run through this. So
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Dr Doug: Dan's giving us some background.
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Dr Doug: and I'm sorry, Diane, which
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Dr Doug: well, I guess you weren't. This was a good question. All right. Let me just read this question from Dan.
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Dr Doug: So Diane's T score is in the negative threes. She's taking strontium as well as hormones. Dexa improved by point 2 and point 4 in 6 months. That's pretty quick.
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Dr Doug: Are you saying? This does not necessarily indicate my bones are getting stronger. Yeah, Diane, that's the rub with strontium.
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Dr Doug: Now, that doesn't mean that it's bad. It just means that we, you know. I wouldn't expect to see significant change in Dexa in 6 months.
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Dr Doug: Where's Diane?
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Dr Doug: I don't see you, Diane. somewhere.
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Dr Doug: Well, anyway, I know you're here. So oh, there you are!
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Dr Doug: So that's the rub with with strontium, is. It's going to improve your Dexa, and some people would say it falsely improves your Dexa. I wouldn't say falsely. It just is improving your Dexa, so how much of that is an improvement in bone strength we don't know, but arguably we never know. So it's heading the right direction. Great keep doing what you're doing.
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Dr Doug: I would recommend getting a rams because rams. I don't think it's gonna be impacted by strontium. If you have access to one
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Dr Doug: we're gonna see improvements in T score. And hopefully, you're gonna see the architecture get better for bone strength. That's why I wish everybody had access to it. Rems but I still recommend it, you know. Add negative 3, 9. I mean, I'd be okay with trontium because we wanna see that that T score get better. There's a there's a mental capacity to that that would be helpful.
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Dr Doug: Let's hear. Alright! So Kim is asking about
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Dr Doug: the vitamin d. She's taking 5,000 of vitamin d. And 300 of K. 2 is MK. 7.
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Dr Doug: She's saying she knows they need to be consumed with a meal containing fat, which is great should they be taken together or separate? Does it matter? So this is one of those controversial things? I think that arguably, if you wanted to have the best absorption of both. You could probably take them separately.
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Dr Doug: it's hard, though, so what I tell my patients is, I would rather you take them together than not take one at all. And most of the products that we use have them together anyway. So all my patients are getting them together. If you can separate them, separate them. If you have that if you have that discipline, I don't. I would forget one
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Dr Doug: so I don't think it matters that much. You also find them together naturally in in the environment. So you find them together in cheese, and you find them together in some, some whole food products. So anytime, I see nutrients that are generally found together, then I'm not as concerned that they're gonna interact because Mother Nature is smarter than that.
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Dr Doug: Let's hear, Susan J. Asked. Supplement person at whole foods recommended
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Dr Doug: bone solid with cell food, essential silica.
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Dr Doug: and has shown improvement of their bone density scores, she said. One lady had reversed osteoporosis. And then you have a link here.
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Dr Doug: yeah. So the silica component, I think, is reasonable. I've looked at that recently, and silica does seem to have an independent impact on bone density. So I think that's totally reasonable. The question is, is, you know how important is it? And you know, is it gonna make the stack? I would say honestly, from most of our patients, it doesn't and we don't even recommend this on a regular basis
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Dr Doug: another. So Susan also asked about another product has a guarantee in his website that if you take his formula exactly, you will never fracture, or you get your money back leaves incremental dosing of vitamin. K throughout the day is the key to not having any fractures. I mean, it's a bold statement, but from a from a business perspective. If you were to just think about this from a business standpoint. That's a really smart play.
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Dr Doug: You're offering people an unbelievable offer and an unbelievable guarantee and the number of people that have osteoproses versus the number of people that fracture. If you just do the statistics on that that's gonna pay off in the long run. So just from a marketing perspective. That's a smart move.
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Dr Doug: is it true? I've never seen any long-term studies on Vitamin K to show that that's true.
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Dr Doug: Sounds cool. So I believe in K, we're obviously providing K, but from a marketing perspective. That's it's wise.
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Dr Doug: I could also say the same thing about our program.
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Dr Doug: join our program, and I guarantee you'll never fracture or your money back. And then I would refund what
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Dr Doug: you know. Maybe 1% of people. some people that have ever fractured on our program.
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Dr Doug: Had one patient fracture while using Osteostrong on our program. That was unfortunate. But she just started so to be fair. Nothing had happened yet.
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Dr Doug: So Diane asked if she could stop the strontium with those scores and see what happens. Yeah, you you can. I would. I mean
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Dr Doug: if I
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Dr Doug: if we decided that we like it, then I would keep using it until we got to a point where we were really solid, you know, like not osteoporotic, or barely
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Dr Doug: If you want to cut down on capsules, then it's a reasonable thing to cut down, because for me again, it. It only makes the stack. I don't know
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Dr Doug: less than 10% of the time.
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Dr Doug: And somebody asked us calcium in your blood from Neutraeval. Show how much
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Dr Doug: you are absorbing. I'd have to look so nutri. Val is a a study that looks at both blood and urine. I'd have to go back and look and see actually what it does show with calcium. I haven't. We haven't used this for that purpose, so II don't know the answer to that.
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Dr Doug: Oh, 1156. Alright, we're gonna do.
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Dr Doug: One more question.
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Dr Doug: Oh, and then this is another question about the garden of life. Grow bone system. Yeah, I've reviewed this a bunch of times. I don't remember the exact components of it. It's fine. It just has a lot of calcium so if you need this much calcium then it's a reasonable product. It's a has a lot of other things in it. So I think it's I think it's a reasonable product. I just concern that there's a lot of calcium that potentially people don't need.